产品货号：
Z28905
中文名称：
UBP43/USP18抗体
英文名称：
Anti-UBP43/USP18 Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-UBP43/USP18 Antibody |
| 指标别名 | UBP43,USP18,ISG43,43kDa ISG15 specific protease,hUBP43,Interferon Stimulated Gene 43kD,ISG15 Specific Processing Protease,ISG43,Ubiquitin Specific Peptidase 18,Ubl carboxyl-terminal hydrolase 18,Ubl thioesterase 18 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB |
| 基因名称 | USP18 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 25-50 of human UBP43 protein. |
| 计算分子量 | 43kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This affinity-purified antibody is directed against human UBP43 protein.The product was affinity purified from monospecific antiserum by immunoaffinity purification.A BLAST analysis was used to suggest reactivity with this protein from human,chimpanzee and orangutan based on 100% homology for the immunogen sequence.The core 7 amino acid sequence QPRERPR of the 10 amino acid immunogen sequence may be reactive with UBP43 from mouse and dog.This core sequence also shows partial homology with proteins other than UBP43.Cross-reactivity with UBP43 homologues from other sources has not been determined. |
| 浓度 | 0.9mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | UBP43 (also known as ISG43,Ubl thiolesterase 18,ISG15-specific processing protease,43kDa ISG15-specific protease,ubiquitin specific protease 18 or USP18) is a member of the deubiquitinating protease family of enzymes,which removes ubiquitin adducts from a broad range of protein substrates.Deletion of the UBP43 gene in mouse leads to a massive increase of ISG15 conjugates in tissues indicating that UBP43 is a major ISG15-specific protease.UBP43 is the first ISG15-specific protease reported.Both ISG15 and UBP43 genes are known to be strongly induced by interferon,genotoxic stress,and viral infection.Thus UBP43 may be necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms. |
| Uniprot ID | Q9UMW8 |
| 基因名全称 | Ubl carboxyl-terminal hydrolase 18 |
| 推荐稀释比 | ELISA:1:10,000 - 1:50,000 IF Microscopy:User Optimized WB:1:500 - 1:2,000 |
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